In a Crowded State, Apalachicola Is the Loneliest Place: Florida's Most Remote Town
Apalachicola, FL — population 3,792, Franklin County — is the most isolated inhabited place in Florida. The nearest city of 10,000+ residents is Panama City, FL, sitting 46 straight-line miles away. Florida has 213 towns under 10,000 residents; Apalachicola is the most isolated among them.
The link opens the SimpleMapLab Map Radius Tool with a 50-mile circle drawn around Apalachicola. Try expanding the radius to see how far you have to look before encountering any 10,000+ city — the answer is roughly 46 miles in the direction of Panama City.
Why this happened
Apalachicola, FL is Florida's most remote inhabited place — but "remote" is relative here: just 46 miles from Panama City. Florida is among the more densely populated US states; the average small-town resident lives 11 miles from a qualifying anchor. Apalachicola's isolation is real to its 3,792 residents, even if the numbers are modest compared to Montana or Nevada.
Florida's 5 most isolated towns
The top 5 most-isolated inhabited places in Florida, sorted by distance to the nearest 10,000+ city.
| # | Town | Pop. | Distance to nearest 10K+ | Nearest city |
|---|---|---|---|---|
| 1 | Apalachicola | 3,792 | 46 mi | Panama City, FL |
| 2 | Eastpoint | 4,409 | 43 mi | Crawfordville, FL |
| 3 | Port Saint Joe | 7,510 | 30 mi | Panama City, FL |
| 4 | Ochopee | 169 | 30 mi | Immokalee, FL |
| 5 | Wewahitchka | 8,838 | 29 mi | Panama City, FL |
How Florida compares
The states ranked closest to Florida on this metric. Click any for the dedicated breakdown.
Draw your own radius
Open a 50-mile circle around Apalachicola →
Try the 100-mile radius to see whether a major city falls inside — for Apalachicola, it doesn't, because the nearest qualifying city (Panama City, FL) sits 46 miles away.
Methodology (brief)
We aggregate the US Census ZCTA dataset by postal city, treating any (postal city, state) pair with ≥ 50 residents as a town. Anchor cities are places with ≥ 10,000 residents. For every Florida town below the anchor threshold, we compute the straight-line distance to every anchor city in the US (cross-state distances count). The town with the largest minimum distance is Florida's loneliest. Full methodology on the hub page.
Suggested citation: SimpleMapLab (2026). The Loneliest Towns in America: Florida. Part of the Most Remote Inhabited Places study. Retrieved from https://www.simplemaplab.com/studies/most-remote-places/florida. CC-BY 4.0.