In a Crowded State, Apalachicola Is the Loneliest Place: Florida's Most Remote Town
Apalachicola, FL — population 3,792, Franklin County — is the most isolated inhabited place in Florida. The nearest city of 10,000+ residents is Panama City, FL, sitting 46 straight-line miles away. Florida has 213 towns under 10,000 residents; Apalachicola is the most isolated among them.
The link opens the SimpleMapLab Map Radius Tool with a 50-mile circle drawn around Apalachicola. Try expanding the radius to see how far you have to look before encountering any 10,000+ city — the answer is roughly 46 miles in the direction of Panama City.
Why this happened
Apalachicola, FL is Florida's most remote inhabited place — but "remote" is relative here: just 46 miles from Panama City. Florida is among the more densely populated US states; the average small-town resident lives 11 miles from a qualifying anchor. Apalachicola's isolation is real to its 3,792 residents, even if the numbers are modest compared to Montana or Nevada.
Florida's 5 most isolated towns
The top 5 most-isolated inhabited places in Florida, sorted by distance to the nearest 10,000+ city.
| # | Town | Pop. | Distance to nearest 10K+ | Nearest city |
|---|---|---|---|---|
| 1 | Apalachicola | 3,792 | 46 mi | Panama City, FL |
| 2 | Eastpoint | 4,409 | 43 mi | Crawfordville, FL |
| 3 | Port Saint Joe | 7,510 | 30 mi | Panama City, FL |
| 4 | Ochopee | 169 | 30 mi | Immokalee, FL |
| 5 | Wewahitchka | 8,838 | 29 mi | Panama City, FL |
How Florida compares
The states ranked closest to Florida on this metric. Click any for the dedicated breakdown.
Draw your own radius
Open a 50-mile circle around Apalachicola →
Try the 100-mile radius to see whether a major city falls inside — for Apalachicola, it doesn't, because the nearest qualifying city (Panama City, FL) sits 46 miles away.
More about Florida
See the full breakdown of Florida's counties at /states/florida/counties — population, area, median income, and county seat for every county, plus a labeled printable map. The companion study 100-mile radius around Florida's capital measures the share of Florida's population that lives within day-trip distance of the capitol — an inverse framing of the isolation question this page poses.
Methodology (brief)
We aggregate the US Census ZCTA dataset by postal city, treating any (postal city, state) pair with ≥ 50 residents as a town. Anchor cities are places with ≥ 10,000 residents. For every Florida town below the anchor threshold, we compute the straight-line distance to every anchor city in the US (cross-state distances count). The town with the largest minimum distance is Florida's loneliest. Full methodology on the hub page.
Suggested citation: SimpleMapLab (2026). The Loneliest Towns in America: Florida. Part of the Most Remote Inhabited Places study. Retrieved from https://www.simplemaplab.com/studies/most-remote-places/florida. CC-BY 4.0.